Saving 2,000 lives a year in Yorkshire by 2025

Yorkshire Cancer Research is committed to investing £100m in ground-breaking research and services, with the ambitious goal of saving 2000 lives a year in Yorkshire by 2025. 

£6.5m 2019 Funding of Research Projects

Since 2015 the Charity has allocated £47m to impactful projects and commissioned work. This year we invite applications for projects (including clinical trials) to our £6.5m 2019 Funding Round to help the people of Yorkshire, avoid, survive and cope with cancer in the following areas:

•    Reducing the risk of developing cancer (including smoking cessation).
•    Early diagnosis and cancer screening.
•    Improving treatments.
•    Supportive and palliative care.
•    Physical activity following a diagnosis of cancer.

The proposed work should have the potential to reduce the risk of cancer, increase cancer specific survival or improve the quality of life of cancer patients during the course of the project. For more information on the above funding priorities please read the 2019 Funding Round announcement.

The deadline for Preliminary applications is 12 noon 8 May.
The following supporting documents are available for you to download:

2019 Funding Announcement

Information for Applicants

Preliminary Form

Full Application by Invitation Only

Please click on the link below for Award Conditions, Policies for Awards and our Ethics Statement.
Please contact research@ycr.org.uk for any questions relating to our research funding or commissioning of health initiatives.

Award Conditions, Polices for Awards and Ethics Statement

The following terms and conditions apply to all applicants applying for funding from the Charity, please read them carefully:

Priorities for 2019 Funding Round

Topic 1: Reducing the risk of developing cancer
37% of cancers are linked to avoidable risk factors such as tobacco, alcohol and obesity [1]. We welcome proposals that consider how we address behavioural, lifestyle and environmental factors to reduce the risk of cancer. The projects must have an interventional element, with the emphasis on solving problems rather than simply describing them. We are happy to receive applications from researcher/practitioner teams engaged in cycles of development and testing to create sustainable change. 

Applications focused on the most commonly diagnosed cancers in Yorkshire will be prioritised as those projects are the most likely to have the greatest impact.

Special consideration will be given to smoking cessation initiatives as lung cancer has the highest mortality rates in Yorkshire and it is estimated that more than 7 in 10 cases are caused by tobacco smoking [1]. 

Topic 2: Early diagnosis and cancer screening
Analysis from The Cancer Taskforce Report, “Achieving world-class cancer outcomes a strategy for England 2015-2020,” and the NHS Long Term Plan indicate that early diagnosis will be the main contribution to 2,000 fewer cancer deaths in Yorkshire. From our own analysis, a 5% stage shift in early diagnosis could result in 87 fewer deaths over one year or 153 fewer deaths over five years in the four most common cancers. Currently an average of 49% of the four most common cancers are diagnosed at an early stage in Yorkshire, this ranges from 29.4% in lung cancer to 80.7% in breast cancer.  If diagnosis of these common cancers achieved the national target for early diagnosis of 75%, there could be a significant improvement for Yorkshire with approximately 1,546 fewer deaths over 1 year or 1,797 fewer deaths over 5 years. 

We welcome applications in the following areas. We will prioritise applications that address the cancers that cause the most deaths in Yorkshire per year, as those projects are most likely to have the greatest impact.

Raising awareness and increasing earlier presentation to primary care
We welcome applications testing interventions that not only raise cancer awareness — especially in hard to reach communities—but also result in an earlier presentation to primary care for people with potential cancer symptoms. Further, we welcome applications that aim to decrease the diagnostic interval for patients, and therefore result in an earlier diagnosis of cancer.

Increasing uptake of national cancer screening programmes
Addressing geographical variations in the uptake rates of national cancer screening programmes across Yorkshire represents an area where significant improvements can be made. We welcome applications to test interventions that can raise the level of cancer screening, especially in areas of greater deprivation, or target identified barriers to attending that can be addressed to improve uptake. 

The introduction of the FIT test for bowel cancer screening increased uptake in Scotland by 8% [2]. We welcome applications testing solutions to accelerate the full implementation of FIT testing in Yorkshire at an optimum sensitivity. For example:
•    Increasing the capacity of the NHS in Yorkshire to undertake more colonoscopies that would allow the FIT threshold to be lowered and the age group to be expanded. 
•    How best to use bowel scope in combination with FIT to understand whether bowel scope and FIT together find and prevent more cancers than FIT alone. 

Please note we expect there will be a year moratorium on research within the bowel screening programme from the time of the full introduction of the FIT test. Any applications approved for funding in this area would only be expected to start in line with the end of the moratorium. 

Testing and implementing new cancer screening 
Applications should focus on the implementation of alternative screening strategies to improve current cancer screening techniques, or identify new approaches that can be implemented for those cancers that are not routinely screened. However tests cannot be in the developmental stage. The project may consider using existing techniques in a novel or adapted way to increase their effectiveness/sensitivity or reduce any negative symptoms associated with the screening technique.

Topic 3: Improving treatments
We welcome applications for clinical trials (see section below) and other studies aiming to test new treatments, or improve current treatments, in order to improve survival and/or quality of life for cancer patients. 

We will prioritise applications that address the most common cancers and those that cause the most deaths in Yorkshire as those projects are most likely to have the greatest impact. 

Topic 4: Supportive and palliative care 
There are currently an estimated 177,000 people living in Yorkshire who have had a diagnosis of cancer, and this number is expected to reach as many as 295,000 people by 2030. 

Many people with a cancer diagnosis do not get the palliative and supportive care they need. By not receiving palliative care at the right time, patients and their families may not have support in place to ensure they have the best quality of life possible, with proper management of physical problems such as pain, as well as emotional issues. We welcome applications aiming to improve access to, or the quality of, supportive and palliative care including end of life care.  

Topic 5: Physical activity following a diagnosis of cancer
By reducing cancer recurrence, secondary prevention through physical activity has the potential to affect Yorkshire’s cancer outcomes. Being physically active after a cancer diagnosis is linked to better cancer outcomes for several cancers [3, 4]. Women who undertook moderate exercise after a breast cancer diagnosis had a 40% to 50% lower risk of breast cancer recurrence. Bowel cancer patients who engaged in leisure time physical activity had a 31% lower risk of death than those who did not. Physical activity after a diagnosis of cancer, especially for cancers with the highest mortality in Yorkshire, could have significant impacts on the number of cancer deaths [5]. 

Proposals for clinical trials 
We welcome applications for clinical trials in any of the above topic areas from feasibility, pilot and complex trials, through to phase I-III trials. 

Trials should attempt to recruit the majority of the study patients from Yorkshire unless this would prohibit the trial due to there not being enough eligible patients in Yorkshire. In this instance, applicants must:
•    Demonstrate that every effort has been made to recruit as many eligible patients from Yorkshire as possible.
•    Outline how many eligible patients there are in Yorkshire and how many the applicants aim to offer the trial to. 

Further to the priorities outlined in the above topic area priority will be given to applications for clinical trials:
•    That will recruit the majority of participants, patients or the public, for the study from within Yorkshire.
•    With the largest ratio of ‘the number of people offered the trial in Yorkshire vs the number of people eligible for the trial in Yorkshire’. 

Cancer Services

If you are involved in commissioning cancer services or service delivery and are interested in testing a new pathway, intervention or service then we would like to hear from you. 

We are interested in working with and funding new service initiatives that support early diagnosis and screening, cancer rehabilitation and smoking cessation. 

Please contact services@ycr.org.uk for further information. 

Travel awards

Only current Award Holders and staff supported by the Charity on Awards greater than one year in length can apply for Travel Awards to present their work at national and international conferences. The maximum Travel Award is £2000. Applicants may apply multiple times for Travel Awards but applications will be prioritised from those who have requested no more than a total of £2000 in a 3 year timeframe. Requests exceeding a total of £2000 in 3 years will only be funded as budgets allow. Applications for costs already incurred will not be accepted.

Travel Award application deadlines are mid-day on 15 March, 15 June, 15 September and 15 December in each year. To apply, please download and complete the application form below and email to research@ycr.org.uk.

Travel Award Application Form

Publication costs award

Funding to cover publication costs is available to a maximum of £2,000 per publication (subject to the availability of funds). If the published work was co-funded, the Charity will contribute a proportionate amount. The Charity must be appropriately acknowledged in all publications where Charity funds have been awarded which have wholly or partly supported the work. Proof of payment should be provided along with a copy of the accepted manuscript when applying for funding to cover publication costs.

Publication Costs application deadlines are mid-day on 15 March, 15 June, 15 September and 15 December in each year. To apply, please download and complete the application form below and email to research@ycr.org.uk.

Publication Costs Award Application Form

Research intellectual property

As a result of the Charity’s strategic shift to focus on areas of investment closer to patients, we have undertaken a further careful analysis of our portfolio and any Intellectual Property (IP) stemming from our funded work. In light of this review, we have made the decision that we will no longer require a formal IP review of papers, abstracts, posters and talks deriving from research awards wholly or partly funded by the charity. Of course, if you do have potential IP issues with your Award which you’d like to discuss with us, please do contact us at research@ycr.org.uk and get in touch with your own Technology Transfer Office.

Changes to Condition 6 of our Award Conditions have been made accordingly. Please note that all other Conditions remain in force. Condition 7 is relevant to the issue of Intellectual Property and commercialisation and is unaffected by this change. Organisations must seek the prior written consent of the charity before it makes any commercial use of, or grants to any third party exploitation rights over charity-funded IP.

 

Research Publicity

All papers deriving from funded work will (along with a Research Publicity Form) need to be submitted to press@ycr.org.uk as a condition of the Award. The papers will be reviewed by our Communications Team so that we can gain internal and external coverage on stories of interest to our donors, stakeholders and the general public. Please email your paper to press@ycr.org.uk 

Our Communications Team will be in touch if they decide to cover your work.

Thank you in advance for helping to promote the important work of Yorkshire Cancer Research.

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